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Key Ingredient Focus: Azelaic Acid

From The Desk of Eugene Korchemniy, R&D, ANFISA Skin.


Azelaic acid stands out as a notable component in our ÂN-DEW 10% Azelaic Acid + PHA Serum. Our meticulous efforts were directed towards formulating a product that exerts a transformative effect on the skin with the ability to harmoniously integrate with other skincare products and ingredients, thus seamlessly accommodating it within any individual's skincare routine. Various skin imperfections, including blemishes, dark spots, uneven texture, congestion, and discoloration, are prevalent concerns encountered by individuals of diverse ages and skin types. Azelaic acid emerges as a multitasking skincare ingredient with extensive compatibility across all skin types and exceptional tolerance, even amongst those with sensitive skin.


What is Azelaic Acid?

Azelaic acid is a compound that can be derived from grains like barley, wheat, and rye. However, the lab-engineered form (gluten-free) of azelaic acid is commonly used in skincare products because it is more stable and effective. This remarkable naturally occurring compound possesses a multitude of benefits for the skin. With its gentle exfoliating properties, it aids in clearing congestion in pores while also reducing the visibility of redness. The profound antioxidative effects of azelaic acid contribute to the reduction of blemishes and the fading of post-acne marks. This exceptional formula works harmoniously to enhance skin clarity, targeting persistent spots and alleviating irritation, ultimately resulting in a smoother, more radiant, and youthful complexion.


Who can benefit?

This remarkable compound offers benefits for individuals struggling with blemishes, uneven skin tone, and rough texture by reducing the appearance of dark spots and promoting a more refined complexion. Moreover, if you find yourself dealing with redness or dryness caused by eczema, azelaic acid can provide soothing relief. It is also suitable for individuals managing rosacea. It's important to note that adverse reactions and side effects to azelaic acid are rare. However, as with any skincare ingredient, if you notice signs of irritation, consider reducing the frequency of use or discontinuing use altogether. Experimenting with less frequent application, such as once every other day, may also be beneficial.




  • Zaenglein AL, Pathy AL, Schlosser BJ, et al. Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology. 2016;74(5):945-973.e33. doi:10.1016/j.jaad.2015.12.037
  • Callender VD, Baldwin H, Cook-Bolden FE, Alexis AF, Stein Gold L, Guenin E. "Effects of Topical Retinoids on Acne and Post-inflammatory Hyperpigmentation in Patients with Skin of Color: A Clinical Review and Implications for Practice." American Journal of Clinical Dermatology. 2021 Nov 9;23(1):69-81. doi: 10.1007/s40257-021-00643-2. PMID: 34751927. PMCID: PMC8776661.
  • Gupta, A. K., & Gover, M. D. (2005). Azelaic acid (15% gel) in the treatment of acne rosacea. International Journal of Dermatology, 44(6), 475–478. doi:10.1111/j.1365-4632.2005.02769.x
  • Lowe, N. J., Rizk, D., Grimes, P., Billips, M., & Pincus, S. (1998). Azelaic acid 20% cream in the treatment of facial hyperpigmentation in darker-skinned patients. Clinical therapeutics, 20(5), 945-959.


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